STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpcB3,4-dihydroxyphenylacetate 2,3-dioxygenase. (285 aa)    
Predicted Functional Partners:
hpcD
5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
 
  
 0.992
betB_3
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.990
mhpD
2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
 
  
 0.971
hpcE_1
4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase.
 
  
 0.956
hpcH
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.956
hpaB
4-hydroxyphenylacetate 3-monooxygenase oxygenase component.
 
 
 0.948
hpaC
4-hydroxyphenylacetate 3-monooxygenase reductase component.
 
 
  0.942
hpcE_2
4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase.
 
  
 0.935
btr
Putative HTH-type transcriptional regulator YobQ.
 
  
 0.921
badR
Homoprotocatechuate degradative operon repressor.
 
   
 0.884
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.