Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hpaC4-hydroxyphenylacetate 3-monooxygenase reductase component. (170 aa)    
Predicted Functional Partners:
hpaB
4-hydroxyphenylacetate 3-monooxygenase oxygenase component.
 
 
 0.997
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
 
  0.943
fre
NAD(P)H-flavin reductase.
  
 
  0.913
ssuE
FMN reductase (NADPH).
    
 0.905
ribF
Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
    
 0.904
ribE
Riboflavin synthase.
    
  0.902
pad1_2
3-octaprenyl-4-hydroxybenzoate carboxy-lyase partner protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
    
  0.900
phoC
Non-specific acid phosphatase.
     
  0.900
feaB_1
Phenylacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.900
ybjI
Flavin mononucleotide phosphatase YbjI.
     
  0.900
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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