Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macA_4Hypothetical protein. (429 aa)    
Predicted Functional Partners:
ybhF_3
Putative ABC transporter ATP-binding protein YhiH.
  
 0.982
yhhJ
Inner membrane transport permease YhhJ.
 
  
 0.973
ybhS
Inner membrane transport permease YbhS.
 
  
 0.805
ybhF_2
Putative ABC transporter ATP-binding protein YbhF.
 
  
 0.779
ybhR_2
Inner membrane transport permease YbhR.
 
  
 0.770
macB
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.684
AML37235.1
Diguanylate cyclase DosC.
       0.526
tolC_2
Outer membrane protein TolC.
  
 
 0.480
mdtP_3
Multidrug resistance outer membrane protein MdtQ.
  
 
 0.436
oprM_2
Outer membrane protein OprM.
  
 
 0.436
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.