Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cusS_3Sensor kinase CusS; Member of a two-component regulatory system. (480 aa)    
Predicted Functional Partners:
cusR_3
Transcriptional regulatory protein CusR.
 0.998
cusF_3
Cation efflux system protein CusF.
 
   
 0.879
cusB_3
Cation efflux system protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.859
ompR
Transcriptional regulatory protein OmpR.
 
 
 0.793
phoP_3
Putative transcriptional regulatory protein YclJ.
 
 0.792
basR_3
Transcriptional regulatory protein BasR.
 
 0.780
yycF
Transcriptional regulatory protein CpxR.
 
 0.769
barA
Signal transduction histidine-protein kinase BarA.
 
 
 
0.766
arcB_1
Aerobic respiration control sensor protein ArcB.
   
 
 0.760
fusA_3
Elongation factor G 1; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
   0.753
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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