STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceAIsocitrate lyase. (434 aa)    
Predicted Functional Partners:
aceB_1
Malate synthase A; Belongs to the malate synthase family.
 
 0.999
aceK_1
Isocitrate dehydrogenase kinase/phosphatase.
 
  
 0.978
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.947
acnB
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
     
 0.942
AML37060.1
Hypothetical protein.
   
 
 0.918
ghrB
Glyoxylate/hydroxypyruvate reductase B; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
     
 0.912
eda
KHG/KDPG aldolase.
     
 0.908
gltA_1
Citrate synthase; Belongs to the citrate synthase family.
   
  
 0.790
maeB_2
NADP-dependent malic enzyme.
   
  
 0.764
pta_1
Phosphate acetyltransferase.
   
  
 0.739
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.