STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrDMultidrug resistance protein D. (394 aa)    
Predicted Functional Partners:
macB
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.633
mdtG
Multidrug resistance protein MdtG.
  
  
 0.612
fieF_4
Cation-efflux pump FieF; Cation-efflux transporter that may have a role in detoxification.
      
 0.547
stp_1
Putative transporter YebQ.
  
   
 0.522
bmr3_2
Putative MFS-type transporter.
  
   
 0.512
hsrA_1
Putative transporter YebQ.
  
   
 0.490
pldA
Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.
  
   
 0.483
AML37867.1
Hypothetical protein.
       0.468
mdfA
Multidrug transporter MdfA.
  
   
0.464
mdlB
Multidrug resistance-like ATP-binding protein MdlB.
  
   
 0.460
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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