STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxCGlutaredoxin-3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (83 aa)    
Predicted Functional Partners:
yibN
Hypothetical protein.
 
  
 0.972
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
 0.966
gpsA_2
Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.889
grxD
Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.744
nrdA
Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.675
nrdE_1
Ribonucleoside-diphosphate reductase 2 subunit alpha.
  
 0.675
trxA
Thioredoxin-1; Belongs to the thioredoxin family.
  
  
 0.663
nrdI
Protein NrdI; Probably involved in ribonucleotide reductase function.
  
  
 0.663
trxB
Thioredoxin reductase.
   
 
 0.662
AML37810.1
ATP synthase subunit b.
  
    0.648
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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