Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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asd_1Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa)    
Predicted Functional Partners:
thrA
Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.992
lysC
Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family.
  
 
 0.984
metL_1
Bifunctional aspartokinase/homoserine dehydrogenase 2.
  
 0.982
dapA_3
4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family.
  
 
 0.957
dapA_1
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.949
AML34586.1
4-hydroxy-tetrahydrodipicolinate synthase.
 
 
 0.946
AML37676.1
4-hydroxy-tetrahydrodipicolinate synthase.
  
 
 0.943
dat_2
Diaminobutyrate--2-oxoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.913
glgB_2
1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
  
 0.736
gltB
Glutamate synthase [NADPH] large chain.
  
  
 0.732
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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