Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
envZ_1Osmolarity sensor protein EnvZ. (453 aa)    
Predicted Functional Partners:
ompR
Transcriptional regulatory protein OmpR.
 0.998
mzrA
Modulator protein MzrA; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
    
 0.940
arcB_1
Aerobic respiration control sensor protein ArcB.
 
 
0.867
ompR_2
Transcriptional regulatory protein OmpR.
 
 
 0.864
ompR_3
Regulatory protein VirG.
 
 
 0.848
phoP_3
Putative transcriptional regulatory protein YclJ.
 
 
 0.807
yycF
Transcriptional regulatory protein CpxR.
 
 
 0.795
arcA
Aerobic respiration control protein ArcA.
 
 
 0.787
phoP_2
Virulence transcriptional regulatory protein PhoP.
 
 
 0.757
barA
Signal transduction histidine-protein kinase BarA.
 
 
0.737
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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