node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaQ | ratA_2 | EAG7_03120 | EAG7_05292 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Persistence and stress-resistance toxin PasT. | 0.470 |
dnaQ | ubiG | EAG7_03120 | EAG7_00353 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.582 |
ispB | ratA_2 | EAG7_04624 | EAG7_05292 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Persistence and stress-resistance toxin PasT. | 0.468 |
ispB | ubiA | EAG7_04624 | EAG7_03814 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.913 |
ispB | ubiF_2 | EAG7_04624 | EAG7_02701 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.400 |
ispB | ubiG | EAG7_04624 | EAG7_00353 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.528 |
ratA_2 | dnaQ | EAG7_05292 | EAG7_03120 | Persistence and stress-resistance toxin PasT. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.470 |
ratA_2 | ispB | EAG7_05292 | EAG7_04624 | Persistence and stress-resistance toxin PasT. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.468 |
ratA_2 | ratB | EAG7_05292 | EAG7_05293 | Persistence and stress-resistance toxin PasT. | Protein RnfH; Belongs to the UPF0125 (RnfH) family. | 0.905 |
ratA_2 | smpB | EAG7_05292 | EAG7_05291 | Persistence and stress-resistance toxin PasT. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.592 |
ratA_2 | sspA | EAG7_05292 | EAG7_04597 | Persistence and stress-resistance toxin PasT. | Stringent starvation protein A; Belongs to the GST superfamily. | 0.590 |
ratA_2 | ubiA | EAG7_05292 | EAG7_03814 | Persistence and stress-resistance toxin PasT. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.646 |
ratA_2 | ubiF_1 | EAG7_05292 | EAG7_04913 | Persistence and stress-resistance toxin PasT. | 2-octaprenylphenol hydroxylase. | 0.668 |
ratA_2 | ubiF_2 | EAG7_05292 | EAG7_02701 | Persistence and stress-resistance toxin PasT. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.617 |
ratA_2 | ubiG | EAG7_05292 | EAG7_00353 | Persistence and stress-resistance toxin PasT. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.729 |
ratA_2 | ubiH_2 | EAG7_05292 | EAG7_04912 | Persistence and stress-resistance toxin PasT. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.554 |
ratB | ratA_2 | EAG7_05293 | EAG7_05292 | Protein RnfH; Belongs to the UPF0125 (RnfH) family. | Persistence and stress-resistance toxin PasT. | 0.905 |
ratB | smpB | EAG7_05293 | EAG7_05291 | Protein RnfH; Belongs to the UPF0125 (RnfH) family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.584 |
smpB | ratA_2 | EAG7_05291 | EAG7_05292 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Persistence and stress-resistance toxin PasT. | 0.592 |
smpB | ratB | EAG7_05291 | EAG7_05293 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Protein RnfH; Belongs to the UPF0125 (RnfH) family. | 0.584 |