Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
icdMonomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (727 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component and related enzymes.
   
 
 0.947
acn
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.942
gdh
Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.857
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.855
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.828
argH
Argininosuccinate lyase.
     
 0.807
gabD1
NAD-dependent aldehyde dehydrogenases.
     
  0.800
ACP32549.1
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
     
  0.800
aspA
Aspartate ammonia-lyase.
     
  0.800
alaT
Aspartate/tyrosine/aromatic aminotransferase.
     
  0.800
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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