Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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hpaF2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene- 17-dioic acid hydratase (catechol pathway). (292 aa)    
Predicted Functional Partners:
fum
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.821
sdhA
Succinate dehydrogenase/fumarate reductase flavoprotein subunits.
  
 
  0.818
sdhB
Succinate dehydrogenase/fumarate reductase Fe-S protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.810
sdhC
Succinate dehydrogenase subunit.
    
  0.804
pthA
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.784
hpaD
Homoprotocatechuate 2,3-dioxygenase; Lactoylglutathione lyase and related lyases.
  
  
 0.722
hpaH
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene- 1,7-dioic acid hydratase (catechol pathway).
  
  
 0.658
hpaE
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 
 0.629
padA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 
 0.616
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
       0.608
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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