STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manPPhosphotransferase system, fructose-specific IIC component. (666 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
ptsF
Phosphotransferase system, fructose-specific IIC component.
 
 
0.998
ptsS
PTS system, sucrose-specific IIBC component; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.996
ptsG
PTS system, glucose-specific IIABC component; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.995
ptsH
Phosphotransferase system, HPr-related proteins.
 
 
 0.992
nagE
PTS system, N-acetylglucosamine-specific IIABC component; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.988
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.982
fda
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.979
dhaM
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Uncharacterized protein conserved in bacteria.
 
  
 0.970
cscK
Sugar kinases, ribokinase family.
  
 
 0.941
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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