Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
acnAconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (938 aa)    
Predicted Functional Partners:
prpC
Citrate synthase; Belongs to the citrate synthase family.
 
 0.995
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
 0.994
sucA
2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component and related enzymes.
 
 0.965
icd
Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
 
 0.942
prpB
PEP phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 0.936
fum
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.931
prpD
Methylcitrate dehydratase; Uncharacterized protein involved in propionate catabolism.
  
 
 0.923
fadB
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase; 3-hydroxyacyl-CoA dehydrogenase.
   
 0.905
rpmF
Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.816
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.799
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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