Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptsHPhosphotransferase system, HPr-related proteins. (89 aa)    
Predicted Functional Partners:
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
ptsF
Phosphotransferase system, fructose-specific IIC component.
 
 
 0.995
manP
Phosphotransferase system, fructose-specific IIC component.
 
 
 0.985
ptsG
PTS system, glucose-specific IIABC component; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
 0.985
ptsS
PTS system, sucrose-specific IIBC component; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
 0.979
nagE
PTS system, N-acetylglucosamine-specific IIABC component; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
 
 0.946
fruK
1-phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.863
ACP33796.1
Transcriptional regulator, LacI family; Transcriptional regulators.
   
 
 0.768
sugR
Transcriptional regulator, DeoR family; Transcriptional regulators of sugar metabolism.
 
     0.445
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.428
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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