Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaE1DNA polymerase III alpha subunit. (1190 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase sliding clamp subunit (PCNA homolog).
  
 
 0.985
dnaX
DNA polymerase III gamma/tau subunits.
 
 0.980
holA
DNA polymerase III delta subunit.
  
 0.980
holB
DNA polymerase III, delta' subunit; ATPase involved in DNA replication.
  
 
 0.978
ACP33224.1
Hypothetical protein.
  
 0.957
dnaQ1
DNA polymerase III epsilon subunit and related 3-5 exonucleases.
   
 0.946
dnaQ2
DNA polymerase III epsilon subunit and related 3-5 exonucleases.
   
 0.943
dnaQ3
DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
   
 0.943
secA1
Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
  
   
 0.747
rarD
Putative RarD protein; Predicted permeases.
     
 0.707
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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