| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACP33864.1 | cysK | cauri_2273 | cauri_2144 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.800 |
| ACP33864.1 | metC | cauri_2273 | cauri_1822 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Cystathionine beta-lyase; Bifunctional PLP-dependent enzyme with beta- cystathionase and maltose regulon repressor activities. | 0.800 |
| ACP33864.1 | pepB | cauri_2273 | cauri_1707 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.900 |
| ACP33864.1 | pepN1 | cauri_2273 | cauri_2032 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Aminopeptidase N. | 0.900 |
| ACP33864.1 | pepN2 | cauri_2273 | cauri_2528 | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Aminopeptidase N. | 0.900 |
| cysK | ACP33864.1 | cauri_2144 | cauri_2273 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.800 |
| cysK | glyA | cauri_2144 | cauri_0929 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.412 |
| cysK | metC | cauri_2144 | cauri_1822 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine beta-lyase; Bifunctional PLP-dependent enzyme with beta- cystathionase and maltose regulon repressor activities. | 0.928 |
| cysK | pepB | cauri_2144 | cauri_1707 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.816 |
| cysK | pepN1 | cauri_2144 | cauri_2032 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aminopeptidase N. | 0.800 |
| cysK | pepN2 | cauri_2144 | cauri_2528 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aminopeptidase N. | 0.800 |
| gcvP | glyA | cauri_1713 | cauri_0929 | Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
| gcvP | pepB | cauri_1713 | cauri_1707 | Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family. | Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.430 |
| glyA | cysK | cauri_0929 | cauri_2144 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.412 |
| glyA | gcvP | cauri_0929 | cauri_1713 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family. | 0.997 |
| glyA | gmk | cauri_0929 | cauri_1182 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.428 |
| glyA | pepB | cauri_0929 | cauri_1707 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.823 |
| glyA | pepN1 | cauri_0929 | cauri_2032 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminopeptidase N. | 0.836 |
| glyA | pepN2 | cauri_0929 | cauri_2528 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminopeptidase N. | 0.836 |
| gmk | glyA | cauri_1182 | cauri_0929 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.428 |
