lipA protein (Corynebacterium aurimucosum) - STRING interaction network

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lipA

Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (363 aa)

Predicted Functional Partners:

lipB

0.999

gcvH

0.965

lplA

0.929

sucB

0.870

ACP33311.1

0.738

gcvP

0.722

sucA

0.698

gcvT

0.647

lpd

0.633

lpdA

0.604

Your Current Organism:

Corynebacterium aurimucosum

NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACP33311.1	gcvH	cauri_1718	cauri_1715	Putative membrane protein.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.546
ACP33311.1	gcvP	cauri_1718	cauri_1713	Putative membrane protein.	Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family.	0.568
ACP33311.1	gcvT	cauri_1718	cauri_1714	Putative membrane protein.	Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.	0.513
ACP33311.1	lipA	cauri_1718	cauri_1717	Putative membrane protein.	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.738
ACP33311.1	lipB	cauri_1718	cauri_1716	Putative membrane protein.	Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.	0.617
ACP33311.1	sucB	cauri_1718	cauri_1711	Putative membrane protein.	Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes.	0.441
gcvH	ACP33311.1	cauri_1715	cauri_1718	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Putative membrane protein.	0.546
gcvH	gcvP	cauri_1715	cauri_1713	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family.	0.999
gcvH	gcvT	cauri_1715	cauri_1714	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.	0.999
gcvH	lipA	cauri_1715	cauri_1717	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.965
gcvH	lipB	cauri_1715	cauri_1716	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.	0.952
gcvH	lpd	cauri_1715	cauri_0254	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes.	0.968
gcvH	lpdA	cauri_1715	cauri_0539	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.	0.766
gcvH	lplA	cauri_1715	cauri_0960	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Lipoate-protein ligase A.	0.939
gcvH	sucA	cauri_1715	cauri_1009	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component and related enzymes.	0.822
gcvH	sucB	cauri_1715	cauri_1711	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes.	0.759
gcvP	ACP33311.1	cauri_1713	cauri_1718	Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family.	Putative membrane protein.	0.568
gcvP	gcvH	cauri_1713	cauri_1715	Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.999
gcvP	gcvT	cauri_1713	cauri_1714	Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family.	Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.	0.999
gcvP	lipA	cauri_1713	cauri_1717	Glycine cleavage system protein P (pyridoxal- binding) C-terminal domain; Belongs to the GcvP family.	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.722

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