| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACP31622.1 | ACP33693.1 | cauri_0023 | cauri_2100 | Rhomboid protease glpG; Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.777 |
| ACP31622.1 | cwlM | cauri_0023 | cauri_2532 | Rhomboid protease glpG; Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Putative hydrolase; N-acetylmuramoyl-L-alanine amidase. | 0.669 |
| ACP31622.1 | tatB | cauri_0023 | cauri_1002 | Rhomboid protease glpG; Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Sec-independent protein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.586 |
| ACP33689.1 | ACP33691.1 | cauri_2096 | cauri_2098 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Metal-dependent hydrolases of the beta- lactamase superfamily III. | 0.807 |
| ACP33689.1 | ACP33693.1 | cauri_2096 | cauri_2100 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.690 |
| ACP33689.1 | ACP33694.1 | cauri_2096 | cauri_2101 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein. | 0.614 |
| ACP33689.1 | ACP33696.1 | cauri_2096 | cauri_2103 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein with SCP/PR1 domains. | 0.414 |
| ACP33689.1 | clpS | cauri_2096 | cauri_2102 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.614 |
| ACP33689.1 | murI | cauri_2096 | cauri_2099 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.965 |
| ACP33689.1 | rphA | cauri_2096 | cauri_2097 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.991 |
| ACP33691.1 | ACP33689.1 | cauri_2098 | cauri_2096 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.807 |
| ACP33691.1 | ACP33693.1 | cauri_2098 | cauri_2100 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.719 |
| ACP33691.1 | ACP33694.1 | cauri_2098 | cauri_2101 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Hypothetical protein. | 0.634 |
| ACP33691.1 | ACP33696.1 | cauri_2098 | cauri_2103 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Uncharacterized protein with SCP/PR1 domains. | 0.446 |
| ACP33691.1 | clpS | cauri_2098 | cauri_2102 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.634 |
| ACP33691.1 | murI | cauri_2098 | cauri_2099 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.719 |
| ACP33691.1 | rphA | cauri_2098 | cauri_2097 | Metal-dependent hydrolases of the beta- lactamase superfamily III. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.846 |
| ACP33693.1 | ACP31622.1 | cauri_2100 | cauri_0023 | Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Rhomboid protease glpG; Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.777 |
| ACP33693.1 | ACP33689.1 | cauri_2100 | cauri_2096 | Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.690 |
| ACP33693.1 | ACP33691.1 | cauri_2100 | cauri_2098 | Uncharacterized membrane protein (homolog of Drosophila rhomboid). | Metal-dependent hydrolases of the beta- lactamase superfamily III. | 0.719 |