Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
hsdMType I restriction-modification system methyltransferase subunit. (590 aa)    
Predicted Functional Partners:
ACP34064.1
Hypothetical protein; Restriction endonuclease S subunits.
 
 
 0.999
mrr
Mrr restriction system protein; Restriction endonuclease.
 
  
 0.940
hsdR
Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.916
ACP34059.1
Hypothetical protein; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.910
ACP31860.1
Hypothetical protein.
  
  
 0.827
ACP34062.1
Putative excisionase.
  
    0.636
ACP34066.1
Hypothetical protein.
       0.552
ACP32614.1
DNA or RNA helicases of superfamily II.
 
   
 0.524
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.473
uvrB
Excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.466
Your Current Organism:
Corynebacterium aurimucosum
NCBI taxonomy Id: 548476
Other names: C. aurimucosum ATCC 700975, Corynebacterium aurimucosum ATCC 700975, Corynebacterium aurimucosum CCUG 48176, Corynebacterium aurimucosum CIP 107436, Corynebacterium aurimucosum CN-1, Corynebacterium aurimucosum DSM 44827, Corynebacterium aurimucosum str. ATCC 700975, Corynebacterium aurimucosum strain ATCC 700975, Corynebacterium nigricans CN-1
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