node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADI66683.1 | folE | HMPREF0573_10364 | HMPREF0573_10367 | Hypothetical protein. | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | 0.630 |
ADI66683.1 | folK | HMPREF0573_10364 | HMPREF0573_10365 | Hypothetical protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.859 |
ADI66683.1 | folP | HMPREF0573_10364 | HMPREF0573_10366 | Hypothetical protein. | Dihydropteroate synthase; COG: COG0294; Pfam: PF00809; InterPro: IPR000489. | 0.835 |
ADI66683.1 | hflB | HMPREF0573_10364 | HMPREF0573_10368 | Hypothetical protein. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.623 |
ADI66683.1 | hpt | HMPREF0573_10364 | HMPREF0573_10369 | Hypothetical protein. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.493 |
ADI66683.1 | tilS | HMPREF0573_10364 | HMPREF0573_10370 | Hypothetical protein. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.458 |
folE | ADI66683.1 | HMPREF0573_10367 | HMPREF0573_10364 | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | Hypothetical protein. | 0.630 |
folE | folK | HMPREF0573_10367 | HMPREF0573_10365 | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
folE | folP | HMPREF0573_10367 | HMPREF0573_10366 | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | Dihydropteroate synthase; COG: COG0294; Pfam: PF00809; InterPro: IPR000489. | 0.999 |
folE | hflB | HMPREF0573_10367 | HMPREF0573_10368 | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.993 |
folE | hpt | HMPREF0573_10367 | HMPREF0573_10369 | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.589 |
folE | tilS | HMPREF0573_10367 | HMPREF0573_10370 | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.576 |
folK | ADI66683.1 | HMPREF0573_10365 | HMPREF0573_10364 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein. | 0.859 |
folK | folE | HMPREF0573_10365 | HMPREF0573_10367 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | 0.999 |
folK | folP | HMPREF0573_10365 | HMPREF0573_10366 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; COG: COG0294; Pfam: PF00809; InterPro: IPR000489. | 0.999 |
folK | hflB | HMPREF0573_10365 | HMPREF0573_10368 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.841 |
folK | hpt | HMPREF0573_10365 | HMPREF0573_10369 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.546 |
folK | tilS | HMPREF0573_10365 | HMPREF0573_10370 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.524 |
folP | ADI66683.1 | HMPREF0573_10366 | HMPREF0573_10364 | Dihydropteroate synthase; COG: COG0294; Pfam: PF00809; InterPro: IPR000489. | Hypothetical protein. | 0.835 |
folP | folE | HMPREF0573_10366 | HMPREF0573_10367 | Dihydropteroate synthase; COG: COG0294; Pfam: PF00809; InterPro: IPR000489. | GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474. | 0.999 |