STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (198 aa)    
Predicted Functional Partners:
ADI67866.1
Hydrolase, alpha/beta domain protein; Pfam: PF00561; InterPro: IPR000073.
 
      0.898
ADI67907.1
ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593.
      0.891
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.832
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
      0.832
ADI66511.1
Single-strand binding family protein; Pfam: PF00436; InterPro: IPR012340.
   
 
 0.691
ADI67029.1
Single-strand binding family protein; COG: COG0629; Pfam: PF00436; InterPro: IPR011344.
   
 
 0.691
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; COG: COG0001; Pfam: PF00202; InterPro: IPR004639.
 
      0.684
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.659
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.620
ADI68217.1
Hypothetical protein.
       0.594
Your Current Organism:
Mobiluncus curtisii
NCBI taxonomy Id: 548479
Other names: Falcivibrio vaginalis ATCC 43063, M. curtisii ATCC 43063, Mobiluncus curtisii ATCC 43063, Mobiluncus curtisii str. ATCC 43063, Mobiluncus curtisii strain ATCC 43063
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