| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| 8D4.130_0 | CIT_0 | A0A367XSY4 | A0A367XZV4 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.973 |
| 8D4.130_0 | FRD1_1 | A0A367XSY4 | A0A367XM24 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Fumarate reductase; Irreversibly catalyzes the reduction of fumarate to succinate. | 0.934 |
| 8D4.130_0 | KGD1 | A0A367XSY4 | A0A367XTY2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 2-oxoglutarate dehydrogenase, mitochondrial. | 0.995 |
| 8D4.130_0 | SDH2_0 | A0A367XSY4 | A0A367Y1C3 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.997 |
| 8D4.130_0 | SHH3_0 | A0A367XSY4 | A0A367YLH6 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Mitochondrial inner membrane protein SHH3. | 0.995 |
| 8D4.130_0 | SHH3_1 | A0A367XSY4 | A0A367XN06 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Mitochondrial inner membrane protein SHH3. | 0.995 |
| 8D4.130_0 | nuo-49 | A0A367XSY4 | A0A367YIH2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | NADH-ubiquinone oxidoreductase subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | 0.953 |
| 8D4.130_0 | nuo-51_0 | A0A367XSY4 | A0A367YQ42 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.801 |
| 8D4.130_0 | nuo-51_1 | A0A367XSY4 | A0A367XPH8 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.801 |
| 8D4.130_0 | nuo78 | A0A367XSY4 | A0A367YLX4 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | NADH-ubiquinone oxidoreductase subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. | 0.920 |
| CIT_0 | 8D4.130_0 | A0A367XZV4 | A0A367XSY4 | Citrate synthase; Belongs to the citrate synthase family. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.973 |
| CIT_0 | FRD1_1 | A0A367XZV4 | A0A367XM24 | Citrate synthase; Belongs to the citrate synthase family. | Fumarate reductase; Irreversibly catalyzes the reduction of fumarate to succinate. | 0.921 |
| CIT_0 | KGD1 | A0A367XZV4 | A0A367XTY2 | Citrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase, mitochondrial. | 0.970 |
| CIT_0 | SDH2_0 | A0A367XZV4 | A0A367Y1C3 | Citrate synthase; Belongs to the citrate synthase family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.994 |
| CIT_0 | SHH3_0 | A0A367XZV4 | A0A367YLH6 | Citrate synthase; Belongs to the citrate synthase family. | Mitochondrial inner membrane protein SHH3. | 0.902 |
| CIT_0 | SHH3_1 | A0A367XZV4 | A0A367XN06 | Citrate synthase; Belongs to the citrate synthase family. | Mitochondrial inner membrane protein SHH3. | 0.902 |
| CIT_0 | nuo-49 | A0A367XZV4 | A0A367YIH2 | Citrate synthase; Belongs to the citrate synthase family. | NADH-ubiquinone oxidoreductase subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. | 0.753 |
| CIT_0 | nuo-51_0 | A0A367XZV4 | A0A367YQ42 | Citrate synthase; Belongs to the citrate synthase family. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.646 |
| CIT_0 | nuo-51_1 | A0A367XZV4 | A0A367XPH8 | Citrate synthase; Belongs to the citrate synthase family. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.646 |
| CIT_0 | nuo78 | A0A367XZV4 | A0A367YLX4 | Citrate synthase; Belongs to the citrate synthase family. | NADH-ubiquinone oxidoreductase subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. | 0.884 |