STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIS61-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (276 aa)    
Predicted Functional Partners:
HIS4
Histidine biosynthesis trifunctional protein.
  
 
 0.999
HIS7_0
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
  
 
 0.996
HIS7_1
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
  
 
 0.996
HIS1
ATP phosphoribosyltransferase.
  
 
 0.993
HIS3_1
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.988
HIS3_0
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.988
RAD16_0
DNA repair protein RAD16.
  
 
 0.985
RAD16_1
DNA repair protein RAD16.
  
 
 0.985
TRP3_0
Multifunctional tryptophan biosynthesis protein.
  
 
 0.978
TRP3_1
Multifunctional tryptophan biosynthesis protein.
  
 
 0.978
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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