| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| 8D4.130_0 | ACH1 | A0A367XSY4 | A0A367YJ69 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acetyl-CoA hydrolase. | 0.990 |
| 8D4.130_0 | CIT_0 | A0A367XSY4 | A0A367XZV4 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.991 |
| 8D4.130_0 | KGD1 | A0A367XSY4 | A0A367XTY2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 2-oxoglutarate dehydrogenase, mitochondrial. | 0.998 |
| 8D4.130_0 | KGD2_0 | A0A367XSY4 | A0A367YLB7 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Dihydrolipoyllysine-residue succinyltransferase. | 0.993 |
| 8D4.130_0 | KGD2_1 | A0A367XSY4 | A0A367YB94 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Dihydrolipoyllysine-residue succinyltransferase. | 0.993 |
| 8D4.130_0 | LSC2_0 | A0A367XSY4 | A0A367XYW6 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |
| 8D4.130_0 | LSC2_1 | A0A367XSY4 | A0A367YA44 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |
| 8D4.130_0 | SDH2_0 | A0A367XSY4 | A0A367Y1C3 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.998 |
| 8D4.130_0 | SHH3_0 | A0A367XSY4 | A0A367YLH6 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Mitochondrial inner membrane protein SHH3. | 0.988 |
| 8D4.130_0 | SHH3_1 | A0A367XSY4 | A0A367XN06 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Mitochondrial inner membrane protein SHH3. | 0.988 |
| ACH1 | 8D4.130_0 | A0A367YJ69 | A0A367XSY4 | Acetyl-CoA hydrolase. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.990 |
| ACH1 | CIT_0 | A0A367YJ69 | A0A367XZV4 | Acetyl-CoA hydrolase. | Citrate synthase; Belongs to the citrate synthase family. | 0.971 |
| ACH1 | KGD1 | A0A367YJ69 | A0A367XTY2 | Acetyl-CoA hydrolase. | 2-oxoglutarate dehydrogenase, mitochondrial. | 0.792 |
| ACH1 | KGD2_0 | A0A367YJ69 | A0A367YLB7 | Acetyl-CoA hydrolase. | Dihydrolipoyllysine-residue succinyltransferase. | 0.740 |
| ACH1 | KGD2_1 | A0A367YJ69 | A0A367YB94 | Acetyl-CoA hydrolase. | Dihydrolipoyllysine-residue succinyltransferase. | 0.740 |
| ACH1 | LSC2_0 | A0A367YJ69 | A0A367XYW6 | Acetyl-CoA hydrolase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.987 |
| ACH1 | LSC2_1 | A0A367YJ69 | A0A367YA44 | Acetyl-CoA hydrolase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.987 |
| ACH1 | SDH2_0 | A0A367YJ69 | A0A367Y1C3 | Acetyl-CoA hydrolase. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.867 |
| ACH1 | SHH3_0 | A0A367YJ69 | A0A367YLH6 | Acetyl-CoA hydrolase. | Mitochondrial inner membrane protein SHH3. | 0.614 |
| ACH1 | SHH3_1 | A0A367YJ69 | A0A367XN06 | Acetyl-CoA hydrolase. | Mitochondrial inner membrane protein SHH3. | 0.614 |
