| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FDH1_6 | FUM1_0 | A0A367Y034 | A0A367YF09 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Fumarate hydratase, mitochondrial. | 0.703 |
| FDH1_6 | FUM1_1 | A0A367Y034 | A0A367XW85 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Fumarate hydratase, mitochondrial. | 0.703 |
| FDH1_6 | MAE1 | A0A367Y034 | A0A367XV89 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | NAD-dependent malic enzyme, mitochondrial. | 0.826 |
| FDH1_6 | MDH1_3 | A0A367Y034 | A0A367Y1M4 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Malate dehydrogenase. | 0.845 |
| FDH1_6 | MDH1_4 | A0A367Y034 | A0A367YBA2 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Malate dehydrogenase. | 0.839 |
| FDH1_6 | PMS1_2 | A0A367Y034 | A0A367YBN8 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Malate synthase; Belongs to the malate synthase family. | 0.724 |
| FDH1_6 | PMS1_3 | A0A367Y034 | A0A367YDE5 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Malate synthase; Belongs to the malate synthase family. | 0.724 |
| FDH1_6 | PYC | A0A367Y034 | A0A367XZ27 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.817 |
| FDH1_6 | YJL068C | A0A367Y034 | A0A367YLW1 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.899 |
| FDH1_6 | trp2 | A0A367Y034 | A0A367XQ21 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Tryptophan synthase. | 0.897 |
| FUM1_0 | FDH1_6 | A0A367YF09 | A0A367Y034 | Fumarate hydratase, mitochondrial. | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 0.703 |
| FUM1_0 | MAE1 | A0A367YF09 | A0A367XV89 | Fumarate hydratase, mitochondrial. | NAD-dependent malic enzyme, mitochondrial. | 0.973 |
| FUM1_0 | MDH1_3 | A0A367YF09 | A0A367Y1M4 | Fumarate hydratase, mitochondrial. | Malate dehydrogenase. | 0.986 |
| FUM1_0 | MDH1_4 | A0A367YF09 | A0A367YBA2 | Fumarate hydratase, mitochondrial. | Malate dehydrogenase. | 0.984 |
| FUM1_0 | PMS1_2 | A0A367YF09 | A0A367YBN8 | Fumarate hydratase, mitochondrial. | Malate synthase; Belongs to the malate synthase family. | 0.915 |
| FUM1_0 | PMS1_3 | A0A367YF09 | A0A367YDE5 | Fumarate hydratase, mitochondrial. | Malate synthase; Belongs to the malate synthase family. | 0.915 |
| FUM1_0 | PYC | A0A367YF09 | A0A367XZ27 | Fumarate hydratase, mitochondrial. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.885 |
| FUM1_0 | trp2 | A0A367YF09 | A0A367XQ21 | Fumarate hydratase, mitochondrial. | Tryptophan synthase. | 0.739 |
| FUM1_1 | FDH1_6 | A0A367XW85 | A0A367Y034 | Fumarate hydratase, mitochondrial. | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 0.703 |
| FUM1_1 | MAE1 | A0A367XW85 | A0A367XV89 | Fumarate hydratase, mitochondrial. | NAD-dependent malic enzyme, mitochondrial. | 0.973 |
