STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYW3_0tRNA wybutosine-synthesizing protein 3. (263 aa)    
Predicted Functional Partners:
trm12_0
tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
 
 
 0.674
trm12_1
tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
 
 
 0.671
TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase.
  
  
 0.641
TRM5
tRNA (Guanine(37)-N1)-methyltransferase.
  
 
 0.636
PPM2_0
tRNA wybutosine-synthesizing protein 4.
  
  
 0.540
PPM2_1
tRNA wybutosine-synthesizing protein 4.
  
  
 0.540
TRM7_1
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
   
  
 0.493
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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