| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| 8D4.130_0 | ERG13 | A0A367XSY4 | A0A367YK63 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.952 |
| 8D4.130_0 | FOX2 | A0A367XSY4 | A0A367YJG1 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Peroxisomal hydratase-dehydrogenase-epimerase. | 0.455 |
| 8D4.130_0 | POX18_1 | A0A367XSY4 | A0A367XQ29 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Oleate-induced peroxisomal protein POX18. | 0.923 |
| 8D4.130_0 | POX4_1 | A0A367XSY4 | A0A367YFN5 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acyl-coenzyme A oxidase 4. | 0.617 |
| 8D4.130_0 | POX4_2 | A0A367XSY4 | A0A367XWV9 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acyl-coenzyme A oxidase 4. | 0.617 |
| 8D4.130_0 | POX4_3 | A0A367XSY4 | A0A367XUH8 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acyl-coenzyme A oxidase 4. | 0.617 |
| 8D4.130_0 | THIKA | A0A367XSY4 | A0A367YA97 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-ketoacyl-CoA thiolase A, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. | 0.950 |
| 8D4.130_0 | THIKB_1 | A0A367XSY4 | A0A367YQ24 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. | 0.950 |
| 8D4.130_0 | THIKB_2 | A0A367XSY4 | A0A367XN02 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. | 0.950 |
| Cantr_05803 | FOX2 | A0A367XPR4 | A0A367YJG1 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | Peroxisomal hydratase-dehydrogenase-epimerase. | 0.494 |
| Cantr_05803 | POX4_1 | A0A367XPR4 | A0A367YFN5 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | Acyl-coenzyme A oxidase 4. | 0.897 |
| Cantr_05803 | POX4_2 | A0A367XPR4 | A0A367XWV9 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | Acyl-coenzyme A oxidase 4. | 0.897 |
| Cantr_05803 | POX4_3 | A0A367XPR4 | A0A367XUH8 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | Acyl-coenzyme A oxidase 4. | 0.897 |
| Cantr_05803 | THIKA | A0A367XPR4 | A0A367YA97 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | 3-ketoacyl-CoA thiolase A, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. | 0.960 |
| Cantr_05803 | THIKB_1 | A0A367XPR4 | A0A367YQ24 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | 3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. | 0.952 |
| Cantr_05803 | THIKB_2 | A0A367XPR4 | A0A367XN02 | Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. | 3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. | 0.952 |
| ERG13 | 8D4.130_0 | A0A367YK63 | A0A367XSY4 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.952 |
| ERG13 | POX18_1 | A0A367YK63 | A0A367XQ29 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Oleate-induced peroxisomal protein POX18. | 0.574 |
| ERG13 | POX4_1 | A0A367YK63 | A0A367YFN5 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acyl-coenzyme A oxidase 4. | 0.477 |
| ERG13 | POX4_2 | A0A367YK63 | A0A367XWV9 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acyl-coenzyme A oxidase 4. | 0.477 |