Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
THIKA3-ketoacyl-CoA thiolase A, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)    
Predicted Functional Partners:
ERG13
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.982
THIKB_2
3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.968
THIKB_1
3-ketoacyl-CoA thiolase B, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.968
POX4_3
Acyl-coenzyme A oxidase 4.
  
 0.962
POX4_2
Acyl-coenzyme A oxidase 4.
  
 0.962
POX4_1
Acyl-coenzyme A oxidase 4.
  
 0.962
Cantr_05803
Putative methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial.
   
 0.960
FOX2
Peroxisomal hydratase-dehydrogenase-epimerase.
  
 0.959
8D4.130_0
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.950
POX18_1
Oleate-induced peroxisomal protein POX18.
  
 0.944
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
Server load: low (14%) [HD]