Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wzcTyrosine-protein kinase; Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)    
Predicted Functional Partners:
wzb
Protein tyrosine phosphatase; Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
 
 0.973
AOE38501.1
Polysaccharide export protein Wza; Required for the translocation of capsular polysaccharide through the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.970
nuoC
NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
     
 0.934
wcaJ_1
UDP-phosphate galactose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.917
wcaJ_3
UDP-phosphate galactose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.866
galF
GalU regulator GalF; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.565
AOE38498.1
Amylovoran biosynthesis protein AmsC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.557
galE
UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
   
 0.534
AOE41823.1
Amylovoran biosynthesis protein AmsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.496
AOE41294.1
Hydrogenase maturation nickel metallochaperone HypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.472
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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