| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOE38688.1 | cysZ_2 | BEE12_01630 | BEE12_01645 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate transporter CysZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.421 |
| AOE38688.1 | ilvC | BEE12_01630 | BEE12_05990 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.430 |
| AOE38688.1 | ligA | BEE12_01630 | BEE12_01635 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| AOE38688.1 | zipA | BEE12_01630 | BEE12_01640 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.646 |
| cysZ_2 | AOE38688.1 | BEE12_01645 | BEE12_01630 | Sulfate transporter CysZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.421 |
| cysZ_2 | ligA | BEE12_01645 | BEE12_01635 | Sulfate transporter CysZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.401 |
| cysZ_2 | zipA | BEE12_01645 | BEE12_01640 | Sulfate transporter CysZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.610 |
| ilvC | AOE38688.1 | BEE12_05990 | BEE12_01630 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| ligA | AOE38688.1 | BEE12_01635 | BEE12_01630 | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| ligA | cysZ_2 | BEE12_01635 | BEE12_01645 | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate transporter CysZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.401 |
| ligA | zipA | BEE12_01635 | BEE12_01640 | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.587 |
| zipA | AOE38688.1 | BEE12_01640 | BEE12_01630 | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.646 |
| zipA | cysZ_2 | BEE12_01640 | BEE12_01645 | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | Sulfate transporter CysZ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| zipA | ligA | BEE12_01640 | BEE12_01635 | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.587 |