| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOE38760.1 | hisS | BEE12_02025 | BEE12_02030 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| AOE38760.1 | ispG | BEE12_02025 | BEE12_02035 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.621 |
| AOE38760.1 | yfgL_2 | BEE12_02025 | BEE12_02020 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Outer membrane protein assembly factor BamB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
| aspS | hisS | BEE12_18410 | BEE12_02030 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| aspS | leuS | BEE12_18410 | BEE12_12280 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.606 |
| aspS | lysS_2 | BEE12_18410 | BEE12_03150 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.600 |
| aspS | thrS_2 | BEE12_18410 | BEE12_15340 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | threonine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.672 |
| aspS | valS_2 | BEE12_18410 | BEE12_09490 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | valine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.829 |
| fmt | hisS | BEE12_04760 | BEE12_02030 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.808 |
| fmt | ispG | BEE12_04760 | BEE12_02035 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.512 |
| fmt | leuS | BEE12_04760 | BEE12_12280 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.439 |
| hisG | hisS | BEE12_00360 | BEE12_02030 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.794 |
| hisS | AOE38760.1 | BEE12_02030 | BEE12_02025 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| hisS | aspS | BEE12_02030 | BEE12_18410 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.903 |
| hisS | fmt | BEE12_02030 | BEE12_04760 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.808 |
| hisS | hisG | BEE12_02030 | BEE12_00360 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | 0.794 |
| hisS | ispG | BEE12_02030 | BEE12_02035 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.865 |
| hisS | leuS | BEE12_02030 | BEE12_12280 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.810 |
| hisS | lysS_2 | BEE12_02030 | BEE12_03150 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.795 |
| hisS | thrS_2 | BEE12_02030 | BEE12_15340 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | threonine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.796 |