STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseAAnti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...] (217 aa)    
Predicted Functional Partners:
rseB
SoxR reducing system protein RseC; Involved in the reduction of the SoxR iron-sulfur cluster; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
rpoE
RNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
 
 0.999
AOE41044.1
RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.869
sspB
ClpXP protease specificity-enhancing factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.842
degS_4
Outer membrane-stress sensor serine endopeptidase DegS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.820
yciS
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.763
lptC
LPS export ABC transporter periplasmic protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.746
degQ_1
Serine endoprotease DegQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.737
degP_2
Serine endoprotease; Protease Do; required at high temperature; degrades damaged proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.737
nlpB
Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.734
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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