Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nrdIIn Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)    
Predicted Functional Partners:
nrdH
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
nrdF
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 
 0.991
nrdB
Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.955
nrdA_1
Ribonucleoside-diphosphate reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.910
nrdD
Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.642
AOE39468.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.559
grxC
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
  
 0.559
grxA
Glutaredoxin; Functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.559
entB
Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.489
AOE39923.1
Integrating conjugative element protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.484
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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