| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| mnmE_2 | obgE | BEE12_07045 | BEE12_09170 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.652 |
| mnmE_2 | rluD | BEE12_07045 | BEE12_02565 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.695 |
| mnmE_2 | rplC | BEE12_07045 | BEE12_04925 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.629 |
| mnmE_2 | rplU | BEE12_07045 | BEE12_09160 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.725 |
| obgE | mnmE_2 | BEE12_09170 | BEE12_07045 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.652 |
| obgE | rluD | BEE12_09170 | BEE12_02565 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.932 |
| obgE | rplC | BEE12_09170 | BEE12_04925 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.875 |
| obgE | rplF | BEE12_09170 | BEE12_04845 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.880 |
| obgE | rplR | BEE12_09170 | BEE12_04840 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.874 |
| obgE | rplS_2 | BEE12_09170 | BEE12_02600 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.926 |
| obgE | rplT | BEE12_09170 | BEE12_15355 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.966 |
| obgE | rplU | BEE12_09170 | BEE12_09160 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.975 |
| obgE | yjgA | BEE12_09170 | BEE12_04280 | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family. | 0.648 |
| rluD | mnmE_2 | BEE12_02565 | BEE12_07045 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.695 |
| rluD | obgE | BEE12_02565 | BEE12_09170 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | ObgE; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.932 |
| rluD | rplC | BEE12_02565 | BEE12_04925 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.710 |
| rluD | rplF | BEE12_02565 | BEE12_04845 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.686 |
| rluD | rplR | BEE12_02565 | BEE12_04840 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.763 |
| rluD | rplS_2 | BEE12_02565 | BEE12_02600 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.768 |
| rluD | rplT | BEE12_02565 | BEE12_15355 | 23S rRNA pseudouridine(1911/1915/1917) synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.724 |