STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabD-2Succinate-semialdehyde dehydrogenase (NADP(+)); Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. (650 aa)    
Predicted Functional Partners:
AOE39198.1
Efflux transporter periplasmic adaptor subunit; With AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.937
aaeX
Transporter; Membrane protein AaeX; the gene is a member of the aaeXAB operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.784
tsx
Nucleoside-specific channel-forming protein Tsx; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
pgpB_1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.714
AOE39159.1
Translocation and assembly module TamB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.695
nlpB
Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.689
tsgA
MFS transporter TsgA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.652
mukB
Cell division protein MukB; SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.643
fhuF
Hydroxamate siderophore iron reductase FhuF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
ampE
Regulatory signaling modulator protein AmpE; Involved in regulation of beta-lactamase; putative signaling protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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