STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (468 aa)    
Predicted Functional Partners:
dnaG_1
DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.942
BEE12_08555
Chromosome partitioning protein ParA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.904
dnaC_2
DNA replication protein DnaC; Acts to load the DnaB helicase onto the initiation site during DNA replication; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.816
dnaA
Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.795
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.725
dnaE_1
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-C family.
 
 
 0.712
umuD
Binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S24 family.
     
 0.630
AOE39910.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.596
ssb
ssDNA-binding protein; Binds to single stranded DNA and PriA helcase facilitate replication restart; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.593
priB
Primosomal replication protein N; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.577
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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