STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degS_4Outer membrane-stress sensor serine endopeptidase DegS; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)    
Predicted Functional Partners:
rseA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...]
  
 
 0.820
ompA
Porin OmpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
    
 
 0.745
degQ_1
Serine endoprotease DegQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.626
rseP
RIP metalloprotease RseP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.540
yhcB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.537
kefB
Glutathione-regulated potassium-efflux system protein KefB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.487
phoE_1
Porin OmpC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.481
phoE_2
Porin OmpC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.467
pnp_2
Polyribonucleotide nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.465
arcB
Aerobic respiration two-component sensor histidine kinase ArcB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.462
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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