| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOE40640.1 | yhbJ | BEE12_12770 | BEE12_09065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNase adaptor protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.831 |
| glmM_2 | yhbJ | BEE12_09275 | BEE12_09065 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | RNase adaptor protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.685 |
| manP | ptsO | BEE12_09715 | BEE12_09060 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.521 |
| manP | rpoN | BEE12_09715 | BEE12_09080 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.463 |
| manP | ulaC | BEE12_09715 | BEE12_16450 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.413 |
| manP | yhbH | BEE12_09715 | BEE12_09075 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosomal subunit interface protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.551 |
| manP | yhbJ | BEE12_09715 | BEE12_09065 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNase adaptor protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.570 |
| ptsN | ptsO | BEE12_09070 | BEE12_09060 | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| ptsN | rne_1 | BEE12_09070 | BEE12_14185 | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.444 |
| ptsN | rpoN | BEE12_09070 | BEE12_09080 | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.831 |
| ptsN | yhbH | BEE12_09070 | BEE12_09075 | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosomal subunit interface protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| ptsN | yhbJ | BEE12_09070 | BEE12_09065 | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNase adaptor protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.843 |
| ptsO | manP | BEE12_09060 | BEE12_09715 | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.521 |
| ptsO | ptsN | BEE12_09060 | BEE12_09070 | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| ptsO | rpoN | BEE12_09060 | BEE12_09080 | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.633 |
| ptsO | yhbH | BEE12_09060 | BEE12_09075 | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosomal subunit interface protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
| ptsO | yhbJ | BEE12_09060 | BEE12_09065 | Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNase adaptor protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.849 |
| rne_1 | ptsN | BEE12_14185 | BEE12_09070 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | PTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |
| rne_1 | rpoN | BEE12_14185 | BEE12_09080 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.460 |
| rne_1 | yhbJ | BEE12_14185 | BEE12_09065 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | RNase adaptor protein RapZ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.757 |