| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BEE12_15430 | cysG_4 | BEE12_15430 | BEE12_02815 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.554 |
| BEE12_15430 | ydiI | BEE12_15430 | BEE12_09175 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Required for efficient enterobactin production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.577 |
| cysG_4 | BEE12_15430 | BEE12_02815 | BEE12_15430 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.554 |
| cysG_4 | ydiI | BEE12_02815 | BEE12_09175 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Thioesterase; Required for efficient enterobactin production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.465 |
| entA | entB | BEE12_09180 | BEE12_09185 | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| entA | entC_2 | BEE12_09180 | BEE12_09195 | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
| entA | entE | BEE12_09180 | BEE12_09190 | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| entA | fepB | BEE12_09180 | BEE12_09200 | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe2+-enterobactin ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.799 |
| entA | ydiI | BEE12_09180 | BEE12_09175 | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Required for efficient enterobactin production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| entB | entA | BEE12_09185 | BEE12_09180 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| entB | entC_2 | BEE12_09185 | BEE12_09195 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| entB | entE | BEE12_09185 | BEE12_09190 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| entB | fepB | BEE12_09185 | BEE12_09200 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe2+-enterobactin ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
| entB | ydiI | BEE12_09185 | BEE12_09175 | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Required for efficient enterobactin production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| entC_2 | entA | BEE12_09195 | BEE12_09180 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
| entC_2 | entB | BEE12_09195 | BEE12_09185 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismatase; 2,3 dihydro-2,3 dihydroxybenzoate synthase; catalyzes the formation of 2,3 dihydro-2,3 dihydroxybenzoate and pyruvate from isochorismate; with Ent DEF is involved in enterobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| entC_2 | entE | BEE12_09195 | BEE12_09190 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| entC_2 | fepB | BEE12_09195 | BEE12_09200 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe2+-enterobactin ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.804 |
| entC_2 | ydiI | BEE12_09195 | BEE12_09175 | Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Required for efficient enterobactin production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.755 |
| entE | entA | BEE12_09190 | BEE12_09180 | Bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
