| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hflB | rlmE | BEE12_09265 | BEE12_09260 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.883 |
| hflB | rplC | BEE12_09265 | BEE12_04925 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.796 |
| hflB | rplJ | BEE12_09265 | BEE12_07845 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.724 |
| hflB | rplV_1 | BEE12_09265 | BEE12_04900 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.787 |
| hflB | rplW | BEE12_09265 | BEE12_04915 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L23; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.542 |
| hflB | rplX | BEE12_09265 | BEE12_04865 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL24 family. | 0.606 |
| ksgA | rlmE | BEE12_10185 | BEE12_09260 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
| ksgA | rplC | BEE12_10185 | BEE12_04925 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.427 |
| ksgA | rplJ | BEE12_10185 | BEE12_07845 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.617 |
| ksgA | rpmD | BEE12_10185 | BEE12_04830 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
| ksgA | rsmB | BEE12_10185 | BEE12_04765 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.706 |
| rlmE | hflB | BEE12_09260 | BEE12_09265 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.883 |
| rlmE | ksgA | BEE12_09260 | BEE12_10185 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.749 |
| rlmE | rplC | BEE12_09260 | BEE12_04925 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.765 |
| rlmE | rplJ | BEE12_09260 | BEE12_07845 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.768 |
| rlmE | rplV_1 | BEE12_09260 | BEE12_04900 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.740 |
| rlmE | rplW | BEE12_09260 | BEE12_04915 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L23; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.741 |
| rlmE | rplX | BEE12_09260 | BEE12_04865 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL24 family. | 0.758 |
| rlmE | rpmD | BEE12_09260 | BEE12_04830 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.850 |
| rlmE | rsmB | BEE12_09260 | BEE12_04765 | Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.779 |