| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOE41899.1 | dmsA_2 | BEE12_08340 | BEE12_09415 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.705 |
| AOE41899.1 | fdoH_1 | BEE12_08340 | BEE12_07155 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
| AOE41899.1 | tufA_1 | BEE12_08340 | BEE12_04950 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.689 |
| AOE41899.1 | tufA_2 | BEE12_08340 | BEE12_07820 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.689 |
| adhB | dmsA_2 | BEE12_09550 | BEE12_09415 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.657 |
| adhB | fdoH_1 | BEE12_09550 | BEE12_07155 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
| adhB | tufA_1 | BEE12_09550 | BEE12_04950 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.689 |
| adhB | tufA_2 | BEE12_09550 | BEE12_07820 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.689 |
| bioB | birA | BEE12_12730 | BEE12_07785 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.936 |
| bioB | dmsA_2 | BEE12_12730 | BEE12_09415 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.900 |
| birA | bioB | BEE12_07785 | BEE12_12730 | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.936 |
| birA | dmsA_2 | BEE12_07785 | BEE12_09415 | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.900 |
| dmsA_2 | AOE41899.1 | BEE12_09415 | BEE12_08340 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.705 |
| dmsA_2 | adhB | BEE12_09415 | BEE12_09550 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.657 |
| dmsA_2 | bioB | BEE12_09415 | BEE12_12730 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.900 |
| dmsA_2 | birA | BEE12_09415 | BEE12_07785 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.900 |
| dmsA_2 | fdoH_1 | BEE12_09415 | BEE12_07155 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Formate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
| dmsA_2 | ftsI_4 | BEE12_09415 | BEE12_09420 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.685 |
| dmsA_2 | gltB_2 | BEE12_09415 | BEE12_09045 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.684 |
| dmsA_2 | oprM_3 | BEE12_09415 | BEE12_09440 | Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.637 |