STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
accA1_3Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1205 aa)    
Predicted Functional Partners:
gatA_4
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
ybgL
Lactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
  
 0.993
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.970
AOE40586.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.947
kipI
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.937
birA
biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.926
AOE41814.1
Cysteine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.922
ttgV
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.919
iclR_2
Transcriptional repressor IclR; Regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.919
iclR_1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.919
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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