node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BEE12_05210 | apt | BEE12_05210 | BEE12_11745 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
BEE12_05210 | gmk | BEE12_05210 | BEE12_06525 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
BEE12_05210 | gpt | BEE12_05210 | BEE12_11090 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine. | 0.900 |
BEE12_05210 | guaA_1 | BEE12_05210 | BEE12_01980 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
BEE12_05210 | guaC | BEE12_05210 | BEE12_10400 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.907 |
BEE12_05210 | hpt | BEE12_05210 | BEE12_10530 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
BEE12_05210 | purA | BEE12_05210 | BEE12_04430 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.903 |
BEE12_05210 | purH_3 | BEE12_05210 | BEE12_07925 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
BEE12_05210 | surE | BEE12_05210 | BEE12_02770 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.909 |
BEE12_05210 | yjjG | BEE12_05210 | BEE12_09910 | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
apt | BEE12_05210 | BEE12_11745 | BEE12_05210 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Intracellular growth attenuator protein igaA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
apt | gmk | BEE12_11745 | BEE12_06525 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.943 |
apt | gpt | BEE12_11745 | BEE12_11090 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine. | 0.933 |
apt | guaA_1 | BEE12_11745 | BEE12_01980 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
apt | guaC | BEE12_11745 | BEE12_10400 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.928 |
apt | hpt | BEE12_11745 | BEE12_10530 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
apt | purA | BEE12_11745 | BEE12_04430 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.520 |
apt | purH_3 | BEE12_11745 | BEE12_07925 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.945 |
apt | surE | BEE12_11745 | BEE12_02770 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.915 |
apt | yjjG | BEE12_11745 | BEE12_09910 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Noncanonical pyrimidine nucleotidase, YjjG family; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |