| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ampD | ampE | BEE12_10425 | BEE12_10430 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulatory signaling modulator protein AmpE; Involved in regulation of beta-lactamase; putative signaling protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| ampD | anmK | BEE12_10425 | BEE12_15605 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.481 |
| ampD | ftsI_3 | BEE12_10425 | BEE12_10305 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.444 |
| ampD | ftsI_4 | BEE12_10425 | BEE12_09420 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.444 |
| ampD | guaC | BEE12_10425 | BEE12_10400 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.610 |
| ampD | hofQ | BEE12_10425 | BEE12_05170 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA transporter HofQ; Outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.671 |
| ampD | mrcA | BEE12_10425 | BEE12_05195 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxypeptidase/penicillin-binding protein 1A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
| ampD | nadC | BEE12_10425 | BEE12_10420 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nucleotide diphosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.604 |
| ampD | nagZ_2 | BEE12_10425 | BEE12_14300 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.490 |
| ampE | ampD | BEE12_10430 | BEE12_10425 | Regulatory signaling modulator protein AmpE; Involved in regulation of beta-lactamase; putative signaling protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| ampE | nadC | BEE12_10430 | BEE12_10420 | Regulatory signaling modulator protein AmpE; Involved in regulation of beta-lactamase; putative signaling protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nucleotide diphosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.602 |
| anmK | ampD | BEE12_15605 | BEE12_10425 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.481 |
| anmK | nagZ_2 | BEE12_15605 | BEE12_14300 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.836 |
| ftsI_3 | ampD | BEE12_10305 | BEE12_10425 | Peptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |
| ftsI_3 | ftsI_4 | BEE12_10305 | BEE12_09420 | Peptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.904 |
| ftsI_3 | mrcA | BEE12_10305 | BEE12_05195 | Peptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Carboxypeptidase/penicillin-binding protein 1A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.510 |
| ftsI_4 | ampD | BEE12_09420 | BEE12_10425 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |
| ftsI_4 | ftsI_3 | BEE12_09420 | BEE12_10305 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Peptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.904 |
| ftsI_4 | mrcA | BEE12_09420 | BEE12_05195 | Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Carboxypeptidase/penicillin-binding protein 1A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |
| guaC | ampD | BEE12_10400 | BEE12_10425 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |