| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOE41813.1 | amtB | BEE12_19270 | BEE12_11650 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| AOE41813.1 | yhjK_1 | BEE12_19270 | BEE12_03715 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.720 |
| amtB | AOE41813.1 | BEE12_11650 | BEE12_19270 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| amtB | dcp_3 | BEE12_11650 | BEE12_16820 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dipeptidyl carboxypeptidase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.628 |
| amtB | glnB | BEE12_11650 | BEE12_02145 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| amtB | glnD | BEE12_11650 | BEE12_10685 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | [protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.651 |
| amtB | glnK | BEE12_11650 | BEE12_11645 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug ABC transporter permease/ATP-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P(II) protein family. | 0.999 |
| amtB | glnL_1 | BEE12_11650 | BEE12_06590 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system sensor histidine kinase NtrB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.785 |
| amtB | gltB_2 | BEE12_11650 | BEE12_09045 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| amtB | gmr_5 | BEE12_11650 | BEE12_17350 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclic di-GMP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.737 |
| amtB | yhjK_1 | BEE12_11650 | BEE12_03715 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
| amtB | zitB | BEE12_11650 | BEE12_12640 | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc transporter ZitB; Involved in zinc efflux across the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.641 |
| dcp_3 | amtB | BEE12_16820 | BEE12_11650 | Dipeptidyl carboxypeptidase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.628 |
| glnB | amtB | BEE12_02145 | BEE12_11650 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| glnB | glnD | BEE12_02145 | BEE12_10685 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | [protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.992 |
| glnB | glnK | BEE12_02145 | BEE12_11645 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug ABC transporter permease/ATP-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P(II) protein family. | 0.732 |
| glnB | glnL_1 | BEE12_02145 | BEE12_06590 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system sensor histidine kinase NtrB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| glnB | gltB_2 | BEE12_02145 | BEE12_09045 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.731 |
| glnD | amtB | BEE12_10685 | BEE12_11650 | [protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
| glnD | glnB | BEE12_10685 | BEE12_02145 | [protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |