| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| holA | lptE | BEE12_12270 | BEE12_12275 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.978 |
| holA | nadD | BEE12_12270 | BEE12_12265 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.975 |
| holA | rlmH | BEE12_12270 | BEE12_12255 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.582 |
| holA | ybeB | BEE12_12270 | BEE12_12260 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.941 |
| lptE | holA | BEE12_12275 | BEE12_12270 | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| lptE | nadD | BEE12_12275 | BEE12_12265 | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.972 |
| lptE | rlmH | BEE12_12275 | BEE12_12255 | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.582 |
| lptE | ybeB | BEE12_12275 | BEE12_12260 | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.937 |
| nadD | holA | BEE12_12265 | BEE12_12270 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| nadD | lptE | BEE12_12265 | BEE12_12275 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.972 |
| nadD | rlmH | BEE12_12265 | BEE12_12255 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.800 |
| nadD | ybeB | BEE12_12265 | BEE12_12260 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.989 |
| rlmH | holA | BEE12_12255 | BEE12_12270 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.582 |
| rlmH | lptE | BEE12_12255 | BEE12_12275 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | LPS assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.582 |
| rlmH | nadD | BEE12_12255 | BEE12_12265 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.800 |
| rlmH | ybeB | BEE12_12255 | BEE12_12260 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.957 |
| rplM | rplN | BEE12_09020 | BEE12_04870 | 50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL13 family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.998 |
| rplM | rplS_2 | BEE12_09020 | BEE12_02600 | 50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL13 family. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.994 |
| rplM | rplT | BEE12_09020 | BEE12_15355 | 50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL13 family. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.998 |
| rplM | rplU | BEE12_09020 | BEE12_09160 | 50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL13 family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.994 |