STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)    
Predicted Functional Partners:
folD
Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.950
glyA_1
Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.937
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
  
0.932
purT_2
Phosphoribosylglycinamide formyltransferase 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.923
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.916
metH_7
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.916
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
    
 0.916
fdoI
Formate dehydrogenase cytochrome b556 subunit; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
fdoH_1
Formate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
mqo_1
Malate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.818
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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