| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOE41843.1 | birA | BEE12_02175 | BEE12_07785 | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.500 |
| AOE41843.1 | hisE | BEE12_02175 | BEE12_00395 | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.937 |
| AOE41843.1 | tilS | BEE12_02175 | BEE12_10790 | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.758 |
| AOE41843.1 | truA | BEE12_02175 | BEE12_01240 | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.631 |
| AOE41843.1 | yeaZ | BEE12_02175 | BEE12_17820 | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| birA | AOE41843.1 | BEE12_07785 | BEE12_02175 | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.500 |
| birA | yeaZ | BEE12_07785 | BEE12_17820 | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.537 |
| dinG-2 | slp | BEE12_17825 | BEE12_17815 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.521 |
| dinG-2 | yeaZ | BEE12_17825 | BEE12_17820 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.656 |
| gcp_1 | tsaE | BEE12_03925 | BEE12_04475 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE; Needed for nucleoid integrity; possibly involved in cell wall synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.868 |
| gcp_1 | yeaZ | BEE12_03925 | BEE12_17820 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |
| hisE | AOE41843.1 | BEE12_00395 | BEE12_02175 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| hisE | yeaZ | BEE12_00395 | BEE12_17820 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.515 |
| paiA | yeaZ | BEE12_09905 | BEE12_17820 | Ribosomal-protein-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.509 |
| slp | dinG-2 | BEE12_17815 | BEE12_17825 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.521 |
| slp | yeaZ | BEE12_17815 | BEE12_17820 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
| tilS | AOE41843.1 | BEE12_10790 | BEE12_02175 | tRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.758 |
| tilS | truA | BEE12_10790 | BEE12_01240 | tRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.654 |
| tilS | yeaZ | BEE12_10790 | BEE12_17820 | tRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
| truA | AOE41843.1 | BEE12_01240 | BEE12_02175 | tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | tRNA adenosine(34) deaminase TadA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.631 |