STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQL43411.1Anti-sigma B factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family. (108 aa)    
Predicted Functional Partners:
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 0.999
KQL43412.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.992
KQL48796.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.991
KQL43413.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.987
KQL43409.1
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.976
KQL50093.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.971
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 0.960
KQL44394.1
Flagellar motor switch protein FliN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.951
KQL46761.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.928
KQL46354.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.858
Your Current Organism:
Brevibacillus choshinensis
NCBI taxonomy Id: 54911
Other names: ATCC 51359, B. choshinensis, Bacillus choshinensis, CIP 103838, DSM 8552, IFO 15518, JCM 8505, LMG 15968, LMG:15968, NBRC 15518, NCIMB 13345, NRRL B-23247, strain HPD52
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