| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KZE39274.1 | KZE39275.1 | AV540_03590 | AV540_03595 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KZE39274.1 | KZE51459.1 | AV540_03590 | AV540_00355 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.783 |
| KZE39274.1 | bioF_2 | AV540_03590 | AV540_05990 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.783 |
| KZE39274.1 | gcvPB_1 | AV540_03590 | AV540_13100 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.972 |
| KZE39274.1 | gcvPB_2 | AV540_03590 | AV540_04460 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.972 |
| KZE39274.1 | glyA_2 | AV540_03590 | AV540_15180 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.864 |
| KZE39274.1 | soxA_1 | AV540_03590 | AV540_09740 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| KZE39275.1 | KZE39274.1 | AV540_03595 | AV540_03590 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
| KZE39275.1 | KZE51459.1 | AV540_03595 | AV540_00355 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| KZE39275.1 | bioF_2 | AV540_03595 | AV540_05990 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.785 |
| KZE39275.1 | gcvPA_2 | AV540_03595 | AV540_04455 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.997 |
| KZE39275.1 | glyA_2 | AV540_03595 | AV540_15180 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
| KZE39275.1 | soxA_1 | AV540_03595 | AV540_09740 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| KZE46853.1 | KZE51459.1 | AV540_21315 | AV540_00355 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
| KZE46853.1 | bioF_2 | AV540_21315 | AV540_05990 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.471 |
| KZE46853.1 | ilvA | AV540_21315 | AV540_14120 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.971 |
| KZE51459.1 | KZE39274.1 | AV540_00355 | AV540_03590 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.783 |
| KZE51459.1 | KZE39275.1 | AV540_00355 | AV540_03595 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| KZE51459.1 | KZE46853.1 | AV540_00355 | AV540_21315 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.837 |
| KZE51459.1 | bioF_2 | AV540_00355 | AV540_05990 | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.790 |
STRING v12.5 is now available!
